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The concept of changing cellular structure and function has been published when a differentiated cell was transformed into a stem cell by introducing 4 key genes [ 49].
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Data on mitochondrial function have been published separately [ 21].
There is no consensus regarding the function of each variant and contradictory results concerning potential function have been published [ 51].
Detailed algorithms for diagnostic approach to children with suspected inherited disorders of platelet function have been published [ 3, 13].
Models on thrombosis or endothelial function have been published before [ 6, 7], but so far none investigated the cAMP mediated signaling in the platelet in detail.
Normal values of cardiac morphology and function have been published for swine but for smaller number of pigs and not for swine whose weights ranged up 100 kg.
Normal values of cardiac morphology and function have been published for dogs [ 5], cattle [ 6], ferrets [ 7], sheep [ 8], monkeys [ 9], Syrian hamsters [ 10], mice [ 11], and rats [ 12].
This is an interesting finding because the lack of a monitoring assay and reversal agent for dabigatran therapy have been important safety concerns for clinicians; cases of bleeding events associated with dabigatran, especially in elderly patients with impaired renal function, have been published in the literature and have received recent regulatory attention in the US and elsewhere [ 24- 28].
A number of complementary reviews on the interplay between DDRs and telomere function have been published recently and are excellent sources for alternative and more detailed views on these and other relevant areas of telomere biology (Verdun and Karlseder, 2007; Longhese, 2008; Rog and Cooper, 2008; Sabourin and Zakian, 2008).
The cytosol of cells is strongly diluted and evidence for degradation of major guard cell functions has been published.
The procedure has been published earlier [25].
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