Sentence examples for function has been evidenced from inspiring English sources
The critical role of filaggrin in epidermis homeostasis and barrier function has been evidenced by the recent disclosure that loss-of-function mutations in the filaggrin gene underlie ichthyosis vulgaris (OMIM #146700) and are strong predisposing factors for atopic dermatitis (OMIM %603165)[10].
The shift in immune system functioning towards a Th2 (or allergy) profile has been evidenced before in GWI and CFS patients [ 22, 41], as has the contrasting position [ 6].
Nonmelanoma skin cancers (NMSC) has been evidenced with an impaired function in nucleotide excision repair (NER).
The key significance of creatine for the energetic metabolism and its other functions in the CNS have been evidenced by creatine deficiency syndromes resulting from inborn errors of creatine synthesis or transport.
Although the biological mechanisms of the impact of PA on β-cell function have not been clarified, there has been evidence that exercises expanded β-cell mass by stimulating its proliferations and preventing its apoptosis (25, 26).
Although in humans no apparent link with ABCC6 (dys)function has been demonstrated, there is some evidence in murine models that Abcc6 is involved in the occurrence of this phenocopy.
Whilst a potential role for the protein phosphatase family of signalling enzymes in mast cell function has been accepted for some time, the evidence has largely been derived from the use of broad specificity pharmacological inhibitors and results often depend upon the experimental conditions, leading to conflicting views.
The potential of dopamine D1 receptor agonists to have beneficial effects on cognitive function has been suggested by a body of preclinical evidence.
The modeling of gene expression that is transcriptionally or translationally activated or repressed by an input signal (see Figure 2) commonly follows this practice, since the shape of the Hill function has been shown to agree well with experimental evidence.
However, up to date no experimental evidence for M6 expression or function has been reported.
