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Remote organ injury, as evidenced by loss of functional capillaries and impaired microvascular function, has been demonstrated in a resuscitated normotensive 24-h chronic model of intra-abdominal sepsis [ 1, 2].
Association of such markers with many traits including diseases like neuronal disorders [ 22] and cancers [ 24] in humans based on expansion/contraction of repeated tracts of microsatellites encoding aminoacid residues in the functional domains of proteins that changes their secondary structure and function has been demonstrated.
The influence of probiotics on brain function has been demonstrated, and this latest research from Oxford has now opened the door for investigation of prebiotic effects.
In the absence of DHA, abnormalities in brain function has been demonstrated (Tapiero et al. 2002).
This is the first time, to our knowledge, that a biological function has been demonstrated for Fst.
These functions are mainly taking place at the cell level and so far no clear function has been demonstrated at the level of the entire organ.
Reduced Ena function has been demonstrated to rescue khc phenotypes-paralytic tail flipping and axonal swellings – in a sensitized Abl background [55].
At a physiological level, the involvement of Dyrk1A in hippocampal function has been demonstrated using transgenic mouse models [21], [39], [40].
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Moreover in rat myocardial infarction models, collaterals and improved cardiac function have been demonstrated using CD34+ stem cell therapy [40].
This assumption is supported by the fact that hitherto all OBPs with identified function have been demonstrated to be expressed only in olfactory tissues.
In Drosophila, dmyc and polycomb (PcG) interact genetically [62] and genes in the trithorax group, that oppose PcG function, have been demonstrated to interact with dmyc genetically and physically [63], [64].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com