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N-terminal fragments of RasGAP, naturally generated by caspase cleavage, exert either an anti-apoptotic function (fragment N, 1 455) or a pro-apoptotic function (fragments N1, 1 157 and N2, 158 455) [3].
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The positions of these intergenic spacers occur at a one-to-one correspondence with the loss-of-function fragments in our speculated gene rearrangement model based on TDRL, providing strong evidence for both our model and the TDRL.
First, it treated all fragmentational debris as spheres of a density which varied as a function of fragment diameter, where diameter was directly related to mass.
Both methods yielded near-identical results for the breakage kernel function with fragment numbers ranging from as many as six in the early stages of the agitation period to two for the smallest surviving parent drops.
They also introduce a similarity function for fragment molecular formulas, which induces a similarity function between nodes of the two trees.
Each experiment was normalized to mean 0 and std of 1, and the smoothed length bias (number of reads as a function of fragment length) was removed.
Third, genotype sets of circuits with more than one function typically fragment into several genotype networks that are disconnected, indicating that such circuits are often mutationally isolated from one another.
We isolated functional fragments of three of the LkARSs (LkARS-E139, LkARS-E848, and LkARS-C35) that are shorter than 100 bp and performed mutagenesis scanning experiments to identify specific sequences necessary for the ARS function of these DNA fragments.
Note that alternative weighting functions of fragment scores or in the linear gap cost model, e.g., affine or non-linear functions, are currently not implemented but are subject to further research.
The RECAP function electronically fragments and recombines molecules based on chemical knowledge of 11 chemical bond types derived from common chemical reactions [27].
However, for a Distributed Database System (DDBS) to function efficiently, fragments of the database need to be allocated carefully at various sites across the relevant communications network.
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