Sentence examples for function events from inspiring English sources

This might imply a smaller number of independent loss of function events, yet selective maintenance of function for at least part of human evolutionary history.

We describe a method for inference of gene function by homology, based annotating gain/loss of function events directly onto a phylogenetic tree.

Conversely, IHC can detect epigenetic loss of function events such as methylation that may be as biologically deleterious as homozygous nonsense mutations.

Identifying these species-specific gain and loss of function events is critical to illuminating the genetic bases for species-specific biology.

This would imply at least 10 independent loss of function events in mammalian evolution, if the phylogeny used in Figure 2 is correct.

The results show that most TPS genes in E. grandis have evolved more than 12 million years ago, but also that there is still ongoing evolution as indicated by novel gene duplication and loss of function events.

This would imply a single loss of function event soon after the origin of ARGFX in the eutherians.

The L58F mutation appears to act as a loss of function event: there is more META1 protein but with a reduced negative effect on SAP activity.

In Cercopithecoidea, we identified several loss-of-function events in KLK2 through a variety of deleterious mechanisms (table 1).

The Wnt pathway is clearly important in many types of human cancer, particularly in epithelial cancer types wherein gain- or loss-of-function events appear to contribute to both inherited cancer risk and somatic carcinogenesis.

The Wnt pathway is clearly important in many forms of human cancer, particularly in epithelial cancer types where gain- or loss-of-function events appear to contribute to both inherited cancer risk and somatic carcinogenesis [ 5].