As reviewed in the subsection on scoring functions, efforts have been made to improve the success rate, including setting a threshold for each target, using consensus scoring functions, or normalizing binding scores.
Notwithstanding the potential limitations of some empirical data in constraining vulnerability functions, efforts are required to improve our estimates of building damage under ash fall loading through the collection of damage data, experimental testing and perhaps theoretical failure analysis.
This human interaction is considered under six concepts; interaction, functional anatomy, human movement, human functions, effort expended as a means of communication, and the environment.
Identifying these requires an honest assessment of the organization to uncover any lagging or missing capabilities or processes that best integrate each function's efforts.
In order to understand how miRNAs function, major efforts have focused on the identification of bona fide target genes.
It is increasingly recognized that perturbational expression compendia are essential to identify the gene networks underlying cellular function, and efforts to build these for different organisms are currently underway.
Along with examining the effect of nanotopography on cell function, consolidative efforts toward characterizing cell type-specific detection limits will be key to understanding and exploiting cell nanotopography interactions for biomedical applications.
As can be seen in their first-order condition given in Eq. (6), where the expected spread is equated to marginal cost of exerting effort, reductions in this spread unambiguously lead to lower effort since the cost of effort is assumed to be an increasing and convex function of effort.
Conditional on a logistical model which expresses costs of soil sampling as a function of effort, and statistical information from which the error of estimates can be modelled as a function of effort, the implicit loss function is the loss function which makes a particular decision on effort rational.
Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown.
