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Any changes to the primary, secondary, tertiary or quaternary structure of a protein can potentially impact its function, efficacy and safety.
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These preliminary results suggest that the efficacy of the programs for the sampling procedure may be ordered as follows: Surflex > Glide-SP > Gold > Glide-XP > FlexX, and for the top-ranking, the scoring functions efficacy as follows: Glidescore ≥ Emodel > PLP > Goldscore > Surflex > FlexX.
Confidence may be influenced by the disclaimer statement required on many DS, which states that the FDA has not approved any health or structure-function efficacy claims made on the label, but says nothing about product safety.
Although functional efficacy was observed in both of the cell-engrafted SCI rats, the results of behavioral analysis showed that the locomotor function and regeneration efficacy of de-ATSC-engrafted SCI rats were restored more significantly, with higher levels of regenerative activity than those of control ATSC-engrafted rats (Figure 6D, 6E).
Objective: To evaluate the contribution of respiratory muscle weakness (part 1) and respiratory muscle training (part 2) to pulmonary function, cough efficacy, and functional status in patients with advanced multiple sclerosis (MS).
Findings of the study indicate (1) improvement in the children's self-image, in both groups, (2) a greater improvement in children's behavior in the experimental group than in the control group, (3) improvement in the functioning and efficacy of parental functioning in both groups (with a higher degree of improvement in the experimental group).
This suggests the two chemical structures are unrelated to each other, giving no hint as to why they have similar biological function and efficacy.
This study reports methods for coating miniature implantable glucose biosensors with electrospun polyurethane (PU) membranes, their effects on sensor function and efficacy as mass-transport limiting membranes.
Among adults with cystic fibrosis, does the timing of hypertonic saline relative to airway clearance techniques affect lung function, perceived efficacy, tolerability, or satisfaction with the entire airway clearance regimen, and is the preferred timing regimen stable over time?
As such, bioprocessing has become a limiting factor in the downstream use of hMSC as non-uniform samples and variation in function impairs efficacy, outcome and application of these advancements.
Influence of thyroid function on efficacy of cancer therapies has been described [ 27].
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