Sentence examples for function effect from inspiring English sources

SNAP was trained on literature-derived [ 16] mutants that are either functionally similar to the wild-type (neutral) or alter function (effect) in either direction (decrease and increase of function).

Cocaine mediates its reinforcing and toxic actions through a "loss of function" effect at multiple receptors.

The geometry function effect and the material degradation effect due to corrosion on the reliability analysis are also investigated.

Over 6 months, aerobic exercise maintained executive function (effect size = −0.11, −0.24, −0.27, and −0.21 for the EXIT-25, BDS, Stroop, and latent factor, respectively).

Ji et al. [39] retrieved the function, effect, and structure knowledge from the titles of IPC.

As our analysis presented here fails to show a gain of function effect for four cancer-derived TRKB point mutations, further research will be required before TRKB can be added to the list of bona fide cancer genes.

In support of this model, we present evidence comprising a predictive correlation and a gain-of-function effect associated with astrocytic depolarization, a predictive correlation and an inhibition/loss-of-function effect associated with astrocytic calcium signaling, and a gain-of-function effect of ChR2, which causes both astrocytic depolarization and calcium signaling.

Altogether, these data provide evidence that the R325G mutation in Kv7.2 reduces PIP2 sensitivity, and that an increased cellular PIP2 levels can rescue the loss-of-function effect prompted by this mutation.

Considering the gain-of-function effect exerted by the P23H mutation, strategies aimed at silencing the expression of the mutated allele, like RNA interference, are desirable.

Mutations of CIAS1 associated with CAPS result in a gain-of-function effect.

It is hypothesised that this gain-of-function effect results in increased Ca2+ influx, and therefore predicts increased neurotransmission.