To understand function requires demonstration of whether the kinase and ROC (GTPase) domains are enzymatically active.
Recent work has revealed a critical role of KNa channels in neuronal function, through demonstration that several mutations in Kcnt1 are associated with intellectual disability and childhood epilepsy (Barcia et al., 2012; Heron et al., 2012; Martin et al., 2014).
Detection of a true decline in renal function requires demonstration of incremental loss of GFR, which may be detected by serial CCl measurements but not initially by serial pCr measurement.
a RBF neural network with classic or cloud Gaussian activation functions; b demonstration of clusters (granules) extracted from data and described by cloud concept; and c description of normal cloud concept.
This was also true for the needs in the SRP dimension (including interface presentation and operation, network functions, teaching demonstration and information updates when elementary and secondary school teachers used e-textbooks in teaching).
The most prominent deficits included higher cognitive functions and particularly demonstration of knowledge, executive functions of planning and working memory, as well as measures of language development such as phonological processing and comprehension.
The analysis would then normally automatically stop at two background functions, but for demonstration we include more functions here.
This article reviews advances in FDSOI technology: device structure, back-bias control function, fabrication process, demonstration of small variability of transistors, reliability including soft error, low voltage circuit design and silicon verification, and improvement in the energy efficiency of CMOS logic circuits.
For example, evidence for a construct of social function could include demonstration of its association with established measures of both physical impairment and social support.
Demonstration of such a link would require a more detailed investigation of how glucose levels affect microglial cellular and molecular function and the demonstration that glycemic control reduces microglial apoptosis.
