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The basis of these and other fluorescence microscopy techniques that have been used to monitor mobility, function, conformations, oligomeric state(s), and/or localization of IDPs in cells are discussed briefly below.
Thus, proteins that are found as conformational ensembles may have more than one functional conformation and multiple functions.
The I.A.A.F. has recently amended its rules to ban devices that vary from the function or conformation of the human body — but it does not ban prosthetic devices per se.
Calmodulin expresses modulating function by conformation change with calcium binding.
Gp41 antigenic function is conformation dependent, therefore we planned to insert a linker sequence onto the MPER core region in order to have the MPER epitope presented on the Ad capsid as close to it's natural conformation as possible [33].
The source function for conformation 1– 180 is consistent with the interpretation of the N H···O interaction as an intermediate to weak H-bond.
*: polymorphism within the race 710 only Seven of the 15 putative CRNs were found to exhibit polymorphisms at the DNA level with a relatively high frequency of non-synonymous changes, leading to modification of the proteins' composition that may result in an alteration of the proteins' function or conformation.
Many types of proteins express their functions with conformation change in various biosystems.
Certain serpins spontaneously undergo the S-to-R transition as part of their function, to form a conformation termed the latent state (Figure 8).
Therefore, we favor a model in which cohesin's functions and conformations could be coordinated by the different states in the hydrolysis cycle of ATPase active sites.
These systems were tested for their ability to avoid macrophage uptake, their complement activation and their pharmacological behavior after systemic injection in mice, as a function of their conformation (neutral or protonated).
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