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Therefore, the problem can be modeled as a simulation optimization problem, where the objective function cannot be evaluated exactly.
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Noise contaminated zero problems involve functions that cannot be evaluated directly, but only indirectly via observations.
Binding of Rfx3 to Abcc8 or voltage-dependent Ca2+ channel genes has not been reported, and although Rfx6 and Rfx3 might coregulate other targets genes, the extent of the functional redundancy of both transcription factors in β cell function and insulin secretion cannot be evaluated, as the phenotype of mice with a deletion of Rfx3 in adult β cells has not been described.
The integral in (13) cannot be evaluated because the integrand function changes in the interval of integration.
Response of non-native plants to disturbance is likely a complex function of a variety of site and landscape factors that cannot be evaluated by the current literature.
Many of these, e.g. the B3 TFs, have not yet been assigned a specific biological function (Table 3), and the significance of their down-regulation in the ashh2 mutant cannot be evaluated at present.
Also, since physical function, the most important endpoint in patients with arthritis, is usually assessed by questionnaires [ 3], disability cannot be evaluated in a similar way in experimental animal models.
The risks cannot be evaluated until we know the bad debts".
Ultimately, however, it cannot be evaluated without regard to other values.
So policymakers' responses cannot be evaluated by short-term measures, either.
Small unmyelinated fibers cannot be evaluated.
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