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The impact of a longer duration of lung function benefit was explored in a sensitivity analysis.
When no lung function benefit is assumed, the ICER amounts to £21,901 per QALY gained.
In the base case analysis, the lung function benefit of roflumilast was limited to 1 year, as observed in studies M2-124 and M2-125.
In this study, it was observed that patients using higher-dose ICS at baseline showed a comparatively greater lung function benefit with FF 200 μg than with FF 100 μg.
The lung function benefit in the model has the impact of indirectly slowing down the progression of disease, and the cost savings in the model are as a result of slowing the progression of patients to the Severe and Very Severe COPD stages.
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A step in the right direction is the certification and labeling system in place for functional foods in Japan, which has the most advanced designation system at present for the health function benefits of food.
If this novel function benefits the organism, the gene will be retained in the genome.
The CATT and IVAN results indicate that ranibizumab and bevacizumab both confer solid visual function benefits.
In summary, the CATT and IVAN results indicate that ranibizumab and bevacizumab both confer solid visual function benefits.
Nearly 40 years of research provides an extensive body of evidence about human health, well-being, and improved function benefits associated with experiences of nearby nature in cities.
An assumption of lung function benefits lasting for 2 and 5 years results in ICERs of £17,712 and £14,889 per QALY gained respectively (Table 6).
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