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We investigated the effects of combining different classifiers to better annotate protein sequences with functional terms defined in the molecular function aspect of GO.
From the molecular function aspect, this review focuses on the impact of KLF14-mediated regulation in major atherosclerosis-related diseases and pathological processes, such as insulin resistance, type 2 diabetes, dyslipidemia, inflammation, obesity, metabolic syndrome, cell proliferation and differentiation.
In this study, we focused on molecular function aspect.
There are also part_of and controlled_by relations in GO but for the molecular function aspect, they were negligible.
First, we formulated the function annotation problem as a classification problem defined on 300 different Gene Ontology (GO) terms from molecular function aspect.
We keep to the molecular function aspect mainly because genes annotated by a MF term are more likely to share a common sequence, subsequence or physicochemical features related to that specific function.
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Studies have shown that uterine EMG can provide valuable information about the function aspects of the uterine contractility [1, 2].
PCA and its treatments affect intimate aspects of a man's bodily and psychological function, aspects that only the man himself and his partner can fully appreciate.
Quite relevant to the theme of present paper are the investigations carried out by Biolek et al. and Yu et al. on the nonlinear and piecewise linear window function aspects for modelling the memristor respectively [16, 17].
3, 4 The burden of IBS on psychosocial, economic, quality of life and daily function aspects is even greater in patients with severe and refractory symptoms.
Our studies are another indication for the variety of structural and function aspects in the GH20 hexosaminidase family important for both catabolism and biosynthesis of glycoconjugates in eukaryotes.
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