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This preconditioning of DCs by calcineurin-inhibiting drugs conceptually integrates the mode of action of CsA with the tolerogenic and T-cell polarization function ascribed to DCs.
Another important function ascribed to SNX2 is in the trafficking of receptors, especially that of Met/HGFR.34 To assess the role of caspase-mediated cleavage of SNX2 on Met signaling, HeLa cells, which express endogenous Met, were transfected with SNX2-specific siRNA, and then treated with HGF (Figure 6a).
The microanatomy and diversity of function ascribed to gills and excretory organs are appraised from an evolutionary perspective, and suggestions made as to future avenues of investigation that may elucidate evolutionary and adaptive trends underpinning the invasion and exploitation of novel habitats.
With respect to mathematical skills, the most common differences pertain to the function ascribed to mathematics.
From the perspective of the autocatalytic and evolutionary dimension of the genetic material, the reproductive function ascribed to genes has turned out to be a function of the whole genome.
One function ascribed to this protein family is non-vesicular cholesterol transfer between the ER and the plasma membrane [21].
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Its function ascribes the AR with a role in prostate oncogenesis.
Annotation of metagenomic fragments against the MG-RAST (Meyer et al., 2008) M5nr database with hierarchical classification revealed 2860 total functional annotations, with 184 unique functions ascribed to samples that did not exceed EPA-BM, compared with 660 in samples that did exceed EPA-BM (Supplementary Figure 3).
The range of functions ascribed to RNA molecules has grown considerably during recent years.
Importantly, structure-guided design of a mutant allele enabled us to dissect the role of EMC in various functions ascribed to Mmi1.
One of the functions ascribed to this protein is the ability to form intracellular membrane-associated foci (MAF), which are believed to be related to the sites of viral replication.
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