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They could also function as linking agents by identifying and connecting with target end-users.
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Independence was used as working correlation matrix with a cumulative logit function as link function.
Independence was used as working correlation matrix and a cumulative logit function as link function.
Previous studies have suggested that ErbB3 and Gab1 can function as links between EGFR and PI-3 kinase.
Note that the Rasch model can be considered as a Generalized Linear Mixed Model with a logistic function as link function.
Regarding directionality, we analyze a system –the TRN of M. tuberculosis[ 12]– for which that is not an actual problem, as regulatory proteins are well identified, i.e. their function as link sources is known.
In particular GRAF1/OPHN-1-L should function as mediator linking the extracellular guiding signals to the intracellular signal transduction pathways that are important for neuronal morphogenesis as well as for cytoskeletal dynamics within neuronal growth cones [ 27].
Because RGS19 is a member of the RGS family that regulates heterotrimeric G-protein signaling, the GIPC1 family of proteins might function as scaffolds linking heterotrimeric G-proteins to receptor tyrosine kinases.
Based on our results we hypothesize that HIF-1α could function as a linking transcription factor for LPS-mediated processes along the tumor invasion from the luminal site to the site of deepest penetration.
Based on different evaluations, a model which used 5 inputs, as well as, 30 chromosomes, 8 head sizes, 2 genes, addition as linking function, RRSE as fitness function while implemented 5 different mathematical operators was selected.
In TEG, clot strength is determined by platelet number and function, as well as cross-linking of fibrin to form a stable clot.
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