Sentence examples for function as initiators from inspiring English sources

Caspase proteins are intracellular proteases which function as initiators and effectors of apoptosis.

An oxidative burst occurs in the early stage of defense responses to pathogen infection [43], suggesting that the generated ROS may function as initiators of cell death in type III necrosis as they do in HR.

Caspases are intracellular proteases that function as initiators and effectors of apoptosis.

Thus, EBV-encoded proteins could function as initiators or cofactors in inducing epigenetic alterations of cell signaling.

The idea of "necroptosis" was demonstrated by a series of subsequent studies in which increasing signal molecules functioning as initiators or effectors of necroptosis such as receptor-interacting protein 1 [ 8] (RIPK1 RIPK1) and receptor-interacting protein 3 [ 9, 10] (RIPK3 RIPK3) or inhibitors such as necrostatin-1 (Nec-1), were discovered.

For instance, many of the HERV sequences could function as transcription initiators and could thus contribute to the pervasive transcription of the human genome [ 51].

Our hypothesis is that in TICs, there is an increase in the expression of these DNA repair-related genes, therefore rendering the cells extremely stable to genetic insult and increasing their ability to survive and function as tumor initiators.

For Dawkins, a beneficiary, by definition, does not simply passively accrue credit in the long term; it must function as the initiator of a causal pathway.

An alternative possibility is that caspase-2 may function as an initiator caspase and effector caspase at the same time.

Such studies also suggest a central role of glucosylceramide in altered macrophage function as an initiator of the disease pathogenesis.

Studies on methionine tRNAs have previously shown that the scaffold sequences determine their function as either initiator or elongator Met tRNA (Von Pawet-Ralmingen et al., 1992; Aström et al., 1993; Kolitz and Lorsch, 2010).