Sentence examples for function as guardian of from inspiring English sources

Two years ago, it formally renounced its "dual function" as guardian of political probity as well as of national security.

"Administrative agencies act as advocates of increased expenditure, and central control organs function as guardians of the treasury" (Wildavsky 1986, p 11 12).

In this context, anti-apoptotic Bcl-2 and Bcl-xL function as guardians of mitochondrial integrity preventing mitochondrial damage and caspase-activation triggered by pro-apoptotic Bcl-2 family members e.g. Bax and Bak at the level of the mitochondria [ 40].

It cannot abdicate its role as guardian of constitutional liberties.

In particular, activation of astrocytes results not only in the production of pro-inflammatory cytokines but also in a decrease in their normal role as guardians of nerve cell function (Steele & Robinson, 2012).

"We take our role as guardians of the beauty of Oxford seriously.

Importantly, we reveal novel findings on the mechanism of threshold activation of p53 pulsatile and oscillatory dynamics that are important for its physiological function as the guardian of the genome.

In an elegant paper published in the July 12 issue of Cancer Cell, Girardini and colleagues show how Pin1-mediated prolylisomerization, a regulatory mechanism intended by evolution to support p53's function as a guardian of the genome, can go haywire and accelerate malignant transformation when p53 carries a dominant-negative mutation.

Specifically we have presented evidence to suggest that while WT p53 might primarily function as the "guardian of the genome" (inducing cells to undergo apoptosis or cell cycle arrest under stress), the WT p53 gene sequence is evolutionarily maintained such that it is susceptible to inactivating mutations and consequent cell survival (with the untoward result of tumorigenesis).

A key function of Bcl-2 is to act as guardian of mitochondrial integrity by opposing pro-apoptotic Bcl-2 family members, and XIAP is also a potent inhibitor of caspases and apoptosis.

But it seems that the function of leukocytes as guardians of the body is reflected in a cautious manipulation of the endothelial cells.