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These lipid mediators function as components of a complex and untapped chemical signaling system that underlies a fundamentally new paradigm of interaction between host and pathogen.
Unlike animals, several of plant ARM proteins function as components of ubiquitin-proteasome system.
Genes and their products function as components of complex networks of macromolecules, which are linked through biochemical or physical interactions.
Proteins generally function as components of complexes that contain other macromolecules, to carry out specific biological processes.
For example, HDACs mediate their biological function as components of larger complexes that include transcription factors and other proteins, offering another layer for pharmacological interventions.
These findings suggest that tetraspanins function as components of insect septate junctions and that their upregulation in CrebA mutants may contribute to the SJ targeting of excess membrane.
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Open image in new window Fig. 7 Partial safety functions as components of safety function Open image in new window Fig. 8 Partial safety functions safety image of the reference track circuit Open image in new window Fig. 9 Partial safety functions safety image of the virtual track circuit.
Other clusters involved complex mechanisms with two or more dominant classes of TFs that may either be activated independent of each other or functioning as components of combinatorial control mechanisms.
These studies establish that Tim-Tipin-Claspin function together as components of the mammalian and yeast replisome that are required for maintaining replication fork stability at programmed pause sites and during conditions of DNA damage.
A substantial portion of these genes function as components or modulators of the ECM or as regulators of the adhesive properties of cells (Table 2).
Now, in his Roman landscapes and scenes of mountain passes and temple ruins, hue and luminosity function in tandem as components of color -- a quality visible in his paintings of the English coast made after his return home.
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