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Gelatin proteins and inorganic silica nanoparticles are incorporated into the material and function as a substrate that helps to accelerate coagulation rates and reduce clotting times.
Although potentially dangerous for genome integrity they are nonetheless a pool of potential regulatory sequences, chromatin control elements, and protein coding genes, and they can function as a substrate for evolutionary processes3,9,21.
To quote a previous manuscript of ours: "The traditional goals of biomedical research function as a substrate for the catalytic activity of translational research that, like an enzyme, is aimed at enhancing the efficiency rather than modifying the process" [5].
Although few BTB-Kelch proteins have been demonstrated to function as a substrate adaptor for a E3 ubiquitin ligase, BTB-Kelch proteins have been demonstrated to have other functions not related to being substrate adaptors of E3 ubiquitin ligases.
Since ENC1 has been shown to form a complex with Cul3-Rbx1 and may also function as a substrate adaptor, it is possible that Nrf2 may also be a substrate for the ENC1-Cul3-Rbx1 E3 ubiquitin ligase.
It has been reported that each of the BTB-Kelch proteins, such as Keap1, ENC1, GAN1 or sarcosin, can function as a substrate adaptor by forming a complex with Cul3-Rbx 1 and is active in targeting self-ubiquitination of BTB-Kelch proteins [43].
Similar(44)
Taken together, these data lead us to postulate that MaviP35 functions as a classical substrate for DRONC, rather than as a suicide substrate inhibitor.
We had previously shown that the PRC barrel is a potential RNA-binding domain [ 18]; in this case it could function as a substrate-binding partner of the Thg1 protein.
Thus, the ABCB15 protein might function as a substrate-specific MDR, The ABCC family comprises 60 full transporters and thus represents the largest family of ABC transporters in T. thermophila.
CRBN functions as a substrate receptor of the Cullin4 (Cubiquitin E3 ubiquitin ligase complex.
Heir, P. et al. DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.
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