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In addition, isolated R1-6 istablele and binds to the C-terminal half of the Nav1.2_ABD with a reasonable affinity (Kd ∼2.3 µM; Figure 5B), supporting that R1-6 can function as a structural unit for Nav1.2 binding.
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Here, we used another approach by defining a family as proteins having the same domain, using the Pfam database [ 21]; protein domains are well-defined regions of a protein that can perform a specific function and form a structural unit [ 22].
These compounds are hydrocarbons that contain a benzene ring as a structural unit.
The first is encoded as a structural unit annotation and the second as an operational annotation.
Thus, we propose that all BAR-PH containing proteins share similar 3D structures in the corresponding regions and that the BAR-PH motif may function as a general structural unit to interact with membrane-bound proteins and other molecular moieties.
This function of introns could occur if exons code for a domain, a polypeptide unit that has a discrete function such as binding to a membrane, the catalytic site of an enzyme, or a structural unit of a protein (Jerry 2001).
The two RRMs (RNA-recognition motifs) of hnRNPA1 form a structural unit that recognizes a G-rich sequence, mediating the function of the protein as an alternative splicing factor as well as a positive (for pri- miR18a) and negative (for pri- let-7a) regulator of pri-miRNA processing [ 23, 37– 37].
A structural unit annotation defines a boundary of a structural unit.
The recycled material was intended initially for interior wall cladding but when pressed together can also function as a structural building material.
Both rutile and anatase belong to the tetragonal crystal system, consisting of TiO6 octahedra as a fundamental structural unit.
HMGB1 is a ubiquitously expressed molecule that functions as a structural protein of chromatin.
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