Leptin, a hormone produced by fat cells, functions as a sentinel of energy balance, and may mediate the putative positive effects of body mass on bone.
We argue that wild bird screening can function as a sentinel system, and we give an example of how it could have been used to forecast a remote and deadly outbreak of influenza A in poultry.
The brown bullhead Ameiurus nebulosus is a species of the family Ictaluridae commonly used as a sentinel of environmental contamination.
Immature DC function as sentinels of the adaptive immune system.
Together with p53, the p16 protein functions as a sentinel that integrates various cellular signals and stresses to limit proliferation.
At Goodman, the sculpture, "6 Standing Glass Panels" (2002/2012), serves as a sentinel for the conundrum of the "STRIPS".
Given their crucial role as sentinels of the innate immune defense, TLR structure and function are tightly regulated [12].
Furthermore, based on our data we suggest that, rather than acting as cell division-count down timers, telomeres function as sentinels of genotoxic and hyperproliferative stresses that stabilize cellular senescence once their structure is compromised.
DCs function as sentinels at sites of invasion and are uniquely programmed to respond to perturbations of homeostasis with a maturation profile that limits bystander activation and targets naïve T-cells circulating through the draining lymph nodes.
Macrophages function as sentinel, cell-regulatory 'hubs' capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state.
