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These results suggest that IDEF1 may function as a sensor of Fe deficiency, in which the signal detection may be determined by the relative concentrations of Fe vs. other metals.
CD163 may be important for controlling inflammation by removing free hemoglobin secondary to hemolysis and converting heme to its anti-inflammatory metabolites, but it also may function as a sensor of bacteria [30].
Thereby FadR protein can function as a sensor of the availability of long chain fatty acid in bacterial growth environment (Cronan & Subrahmanyam, 1998, DiRusso et al., 1998, Campbell & Cronan, 2001).
P1 therefore seems to function as a sensor for the peptide load where occupation leads to a stabilization of the 'open' conformation required to accommodate the peptide ligand.
Although plant PII orthologs were speculated to function as a sensor for both C and N [31], the T-DNA knockout mutants of GLB1 exhibit only weak phenotypes [32].
To function as a sensor, metal binding must alter either the electronic structure or the molecular structure of the sensor.
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Nb2O5 supported on TlO2 functioned as a sensor for oxygen and nitrogen monoxide.
This paper describes a SCS prototype that functions as a sensor and actuator for scientific research and potential clinical applications.
The human pregnane X receptor (PXR) is a promiscuous nuclear receptor that functions as a sensor to a wide variety of xenobiotics and regulates expression of several drug metabolizing enzymes and transporters.
It was later shown that UPR could be activated in response to both glucose and oxygen deprivation thus functions as a sensor for cell energy status (Kauffman et al., 2002).
Together, these data suggest that YopK functions as a sensor and mediator of productive effector translocation.
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