Sentence examples for function as a catalytic component from inspiring English sources

A protein called ARGONAUTE is known to function as a catalytic component of the RNA-induced silencing complex, which targets mRNA for degradation using miRNA as a guide [ 46].

RING domains function as the catalytic component of E3 ubiquitin ligases - enzymes that catalyze the final step in the attachment of ubiquitin to substrate proteins and are believed to confer specificity to the ubiquitination process [ 5].

It has been suggested that this C-terminal domain may function as a catalytic domain for these PPR proteins [ 6].

The catalytic center of these proteins are known to possess three conserved metal chelating amino acid residues in the PIWI domain i.e. aspartate, aspartate and histidine (DDH) that function as a catalytic triad.

ARD1 functions as a catalytic subunit of the N-terminal protein acetyltransferase complex [20], [22], [28].

The PBP2a active site contains a nucleophilic Ser403, while the backbone nitrogens of Ser403 and Thr600 form a conserved oxyanion hole, and Lys406 functions as a catalytic base[6].

The Ser in this sequence functions as a catalytic residue and constitutes a 'catalytic triad' together with the conserved Glu and His residues that are presumed to facilitate the hydrolysis [ 16].

On one hand, and as expected from the canonical function of TERT as the catalytic component of telomerase, mice treated with AVV9-mTERT vectors showed telomere elongation in a variety of tissues, which was concomitant with a significant decrease in the abundance of short telomeres, in turn responsible for chromosomal aberrations (Hemann et al, 2001; Samper et al, 2001).

The well documented and conventional function of TERT is its role as the catalytic component of telomerase which is indispensable for the maintenance of telomeres, and thus genome integrity [7].

Therefore Cas5c seems to be able to function as both a catalytic Cas6 equivalent and a structural Cas5 equivalent.

Yang, J. S. et al. ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat.