Sentence examples for function as a catalytic from inspiring English sources

Thus, a glutamic acid at position 363 appeared to function as a catalytic base to enhance cyclosarin reactivation; a glutamine in that position failed to stimulate enzyme activity in the presence of cyclosarin.

It has been suggested that this C-terminal domain may function as a catalytic domain for these PPR proteins [ 6].

On the cytoplasmic side, Dappu-Trk includes a tyrosine kinase (TK) domain that has all the key residues necessary to carry out its function as a catalytic receptor.

During this process of sequence-specific cleavage, three conserved metal-chelating residues in the PIWI domain play critical roles and function as a catalytic triad [ 16, 20].

From the highly conserved PIWI domains, we detected conserved Asp-Asp-His (DDH) motifs that function as a catalytic triad and have critical roles during the process of sequence-specific cleavage in the RNAi machinery.

A protein called ARGONAUTE is known to function as a catalytic component of the RNA-induced silencing complex, which targets mRNA for degradation using miRNA as a guide [ 46].

ARD1 functions as a catalytic subunit of the N-terminal protein acetyltransferase complex [20], [22], [28].

The PBP2a active site contains a nucleophilic Ser403, while the backbone nitrogens of Ser403 and Thr600 form a conserved oxyanion hole, and Lys406 functions as a catalytic base[6].

Our studies suggest a revised paradigm for tubulin cofactors and Arl2 functions as a catalytic chaperone that regulates soluble αβ-tubulin assembly and maintenance to support microtubule dynamics.

The Ser in this sequence functions as a catalytic residue and constitutes a 'catalytic triad' together with the conserved Glu and His residues that are presumed to facilitate the hydrolysis [ 16].

For example, hBChE variant G117H increased the rate of hydrolytic dephosphonylation of nerve agent hBChE covalent adducts and functioned as a catalytic bioscavenger by converting reactive nerve agents to relatively inert products through a net hydrolysis reaction.