We propose that BEAD-1 functions as a boundary that separates the TCR alpha/delta locus into distinct regulatory domains controlled by Edelta and the TCR alpha enhancer, and that it prevents Edelta from opening the chromatin of the TCR alpha joining gene segments for VDJ recombination at an early stage of T cell development.
The results implied that the carrier mobility of a nanowire less than 1 μm in diameter was significantly reduced compared with that for a bulk bismuth sample due to the collision at the quartz template surface, which functioned as a boundary condition, as a result of the classical size effect [25, 26].
The patient appointment booking system functioned as a boundary object in this context [ 6, 7].
18 The tight junction functions as a boundary to distinguish apical and lateral domains, and as a barrier to protect against unselective passage in the intercellular space.
This conserved region is a known regulatory element and functions as a boundary element in neural tissue to prevent expression of Hoxd genes.
While functioning as a boundary lubricant in articular joints, lubricin is also recognized to have a major protective role in preventing cartilage wear, and synovial cell adhesion and proliferation [ 7].
If H3K9me3 functions as a boundary marker or an antagonizing marker for CENP-A, why does a protein that is recruited to the centromeric chromatin in a Suv39h-dependent manner play a major role in directing the Mis12C complex to the kinetochore?
More importantly, we show that personalities (e.g., agreeableness) could function as a crucial boundary condition for turning emotions (e.g., envy) into behaviors (e.g., ostracize others), providing a more comprehensive understanding of emotions in the workplace.
This observation suggests that TARE 5 may function as a sequence boundary element separating telomeres from coding regions.
In agreement with this, developmentally regulated activation of a SINE element in mammals was recently shown to function as a domain boundary [ 38].
