Sentence examples for function and gain from inspiring English sources

He also said he expected Rodriguez's hip to return to full function and gain more range of motion.

B52 activity is critical for Drosophila development as both loss of function and gain of function lead to lethality [35].

We next used both loss of function and gain of function approaches to study the role of Prdm5 during zebrafish development.

Additional work on the Thr946Ala SNP is therefore necessary to discover how it alters IFIH1 function and gain insight on how it affects T1D pathogenesis.

However, once NK cells lyse a proportion of sensitive targets they lose their cytotoxic function and gain the ability to secrete cytokines (split anergy) required to support differentiation of the cells not lysed by the NK cells.

Since genes may have several functions that are controlled by different regulatory regions, when a specific subset of the gene function is subjected to a degenerative mutation, it may lose this given function and gain a new one.

Phenotype-driven genetic screens with loss-of function and gain-of function methods have been successfully used to discover reprogramming factors.

Gene redundancy can make it difficult to design experiments based on loss of biological function, and gain-of-function approaches offer an interesting alternative.

Since mutant p53 confers both loss of WT p53 function, and gain-of-function effects on a large number of target genes [ 23, 27, 28], we asked whether Toca-1 expression was induced or dependent on mutant p53 expression.

A functional genetic screen using loss-of-function and gain-of-function alleles was performed to identify modifiers of tau-induced neurotoxicity using the 2N/4R (full-length) isoform of wild-type human tau expressed in the fly retina.

It is noticeable that sodium channelopathies can be attributed to both loss-of-function and gain-of-function mutations.