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Two-dimensional echocardiography shows areas of the left ventricle that function abnormally.
Some megaloblasts mature to become large red blood cells called macrocytes; they reach the circulation but function abnormally.
A diagnosis of rhabdomyolysis may be suspected in anyone who has suffered trauma, crush injury or prolonged immobilization, but it may also be identified at a later stage due to deteriorating kidney function (abnormally raised or increasing creatinine and urea levels, falling urine output) or reddish-brown discoloration of the urine.
Together these data support a model where protein components are localized to the nuclear membrane but where we anticipate that they function abnormally similar to what we previously noted with nesprin-1 mutations [30], [31].
In general, the tumor vessels increase in density over time, and they also function abnormally.
The neovasculatures in gliomas function abnormally with irregularity of the endothelial lining and disruption of the blood-brain barrier (BBB) [ 57, 58].
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"Personality is an expression of brain function, so if a brain functions abnormally then it will impact on personality.
I believe we should be thinking more anatomically and asking, "With schizophrenics, which brain regions are functioning abnormally?" Q. ARE YOU WORRIED YOUR FINDINGS MIGHT BE MISUSED? A. The reason I sat on these findings for a couple of years was that I just wanted to be absolutely sure it was true.
"With respect to the neuroimaging data, while [the Court] find[s] that the data demonstrates that areas of the defendant's brain are functioning abnormally, Dr. Gur's testimony did not convince the Court that the totality of the defendant's brain abnormalities would lead to a diagnosis of sufficiently sub-average intelligence".
The brain scans show which areas of the addict's brain are functioning abnormally, and how badly affected they are.
The mutant cTnT protein likely incorporates into the sarcomere along with a smaller amount of wildtype protein and functions abnormally, leading to DCM.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com