Strikingly, Slc6a3 gene therapy was able to fully rescue the similarly altered HVA/5-HIAA ratio in DAT-KO mice, thus directly validating this approach for future translational studies in humans.
Exogenous expression of TYRA-2 under its own promoter could fully rescue its feeding suppression defect (Fig. 1C).
Exogenous expression of TYRA-2 under its own promoter or specifically in AIM interneurons could fully rescue its feeding suppression defect in the tyra-2 mutant.
And finally, if a viewer is experiencing difficulty segmenting due to disruptions in perceptual processing, error monitoring, or event model maintenance, then the intervention may not be able to fully rescue their performance.
However, IFNγ prelicensed thawed MSCs do not deploy lung tropism in vivo following intravenous injection as well as fresh MSCs suggesting that IFNγ prelicensing does not fully rescue thaw-induced lung homing defect.
Nevertheless, it can fully rescue the BrdU incorporation defects and the sensitivity to gamma irradiation of the mutant.
The full length dRecQ4 is able to fully rescue dRecQ414 mutant to adulthood without any obvious defects.
These genetic data support the hypothesis that germline-specific expression of DAZL is sufficient to fully rescue male fertility in DAZL-deficient mammals.
Under conditions of endogenous ATG16L1 ablation, expression of ATG16L1*300A failed to fully rescue autophagy of S. Typhimurium, whereas ATG16L1*300T yielded robust anti-Salmonella autophagy.
In either case, in absence of dioxin, Ahr would not be able to disrupt normal development or fully rescue ss− phenotypes as Ss and hyperactive Ahr do.
Remarkably, the over-expression of p57Kip2 in sik1flp/flp cells was able to fully rescue the cardiac phenotype, as shown by FACS and qPCR analysis.
