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Unlike other previously characterized Fe(II)/αKG enzymes, turnover in FIH is fully limited by the rate of O2 activation.
Prior to in-vivo testing with human patients, it would be reasonable to subject the probe to further destructive tests to confirm the failure mode of the device will not involve sudden surge of output current, transient or permanent, and fully limited by the upper bound of the power source driving the probe.
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Results of these studies indicate that large NPP plants as considered here can have significant penetration into the moat wall, and thus not fully limit displacements in the isolation system, while having considerable increases in accelerations throughout the height of the NPP model.
As the president contemplates striking Syria, the public deserves to understand more fully what "limited" military action actually means.
Considering that our plants were more established than these studies prior to Fe deficiency, it is possible that our six week old plants were not fully Fe limited at the time of sampling and this may have reduced the induction ratios that we observed.
Our ability to define glycemic responses fully was limited by the study design, optimized to evaluate drug effects on lipids and safety.
Nevertheless, we propose that the loss of HOXB13 may be an additional important event for CRC cells, conferring a growth advantage to fully utilise limited TCF4 and subsequently overexpress its downstream genes.
The present work presents a fully integrated limiting equilibrium process for design of reinforced soil retaining structures.
However, in spite of its technological benefits the effects of porosity on BPM fracture strength and Weibull statistics are not fully understood, limiting the wider use of these materials.
Some assays were modified by altering the concentration of coupling enzymes or other reagents to ensure that the rate measured is the rate of the reaction of interest (fully rate limiting).
Although cell surface PRRs such as the TLRs 2, 4, and 9 have been implicated in the response to A. fumigatus in the airway, their roles and PAMPs to which they respond have not been fully established limiting the attractiveness of developing therapy on their basis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com