Sentence examples for fully impair from inspiring English sources

In contrast to our results, another study reported that mutation of either the SD or the SH3 binding motif of the SBD was sufficient to fully impair p130Cas-enhanced cell migration [26] and thus a distinct role for the SBD could not be attributed.

Whilst the dominant negative Rab5aS34N did not show decreased interaction with the hIP or fully impair internalization, it prevented hIP sorting to endocytic vesicles.

According to the oocyte experiments, additional mutations of S1 – S3 would be needed to fully impair basipetal auxin transport but such an experiment would not allow us judging the importance of the previously uncharacterized S4 phosphosite.

These findings extend LCs knowledge indicating that they are not fully impaired by melanoma, contributing to design new LCs-based therapeutic approaches.

Here, we show that Piezo1 is highly expressed in myocytes of small-diameter arteries and that smooth-muscle-specific Piezo1 deletion fully impairs SAC activity.

CAT mRNA turnover was fully impaired during early recovery, suggesting that stabilisation of CAT mRNA as well as stimulation of the hormonal activation of CAT gene transcription account for the thermal enhancement of glucocorticoid-induced CAT expression.

Loss of either signaling function fully impaired p130Cas-enhanced rates of plasma membrane protrusion and FA assembly/disassembly.

The laz1-5 mutation suppressed the extent of cell death elicited by Pst DC3000 (avrRps4) to comparable levels as the enhanced susceptibility eds1 and rar1 controls which are either fully impaired or compromised in RPS4-conditioned HR [4], [22] (Figure 4A).

Neither the 15F mutation (loss of tyrosine phosphorylation sites) in the SD nor the mPR mutation (disruption of the Src SH3-binding motif) in the SBD fully impaired the ability of p130Cas to promote cell migration.

Indeed, cell death triggered by FasL was fully impaired in I9-2e (caspase-8 and -10-doubly deficienot, but not in I9-2d (caspase-8-deficient but caspase-10-proficient) Jurkat cells.

As expected, wild type Col-0 plants exhibited high levels of electrolyte leakage, while the laz1-5 mutation suppressed the extent of cell death, but not to the level of the rar1 mutant, which is fully impaired in RPM1 conditioned HR [22] (Figure 4C).