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Further studies will clearly be necessary to fully define the interactions between VDR signaling, metabolism, adipose and aging.
Further studies will be required to fully define the role of the mpt in L. monocytogenes.
These three parameters together fully define the equilibrium state and thus completely specify the pH titrations.
Another way to define the interaction similarity is through the similarity of the corresponding interaction interfaces.
This work further demonstrates the robustness of sulfoxide-containing MS-cleavable cross-linkers in XL-MS studies and provides a strong basis for us to further develop new DSSO derivatives and fully define protein protein interactions.
As a system to test the capacity of peptoids to inhibit the interaction of Ubc13 with Uev1, we used the yeast-two hybrid assay, since it permits to readily determine the specificity of the inhibitory activities on a fully defined protein-protein interaction and, simultaneously, it constitutes a stringent filter for the bioavailability of active molecules.
He added that the State Senate bill did not fully define "political purposes".
Of particular importance, Mn shows selective neurotoxicity to DAergic neurons by mechanisms that have yet to be fully defined but possibly involve interaction with DA, leading to its oxidation forming toxic quinones and consequent oxidative stress [ 45– 45].
The Cac-derived peptide bound to SH3-III is fully defined in the electron density.
The fully defined Def1 processing system should prove helpful in further defining the underlying mechanisms.
The nature of the interactions between neighboring RyRs and/or with associated proteins has not been fully defined, but it is likely that electrostatic interactions may play a role as the vestibule of RyRs contain negatively charged regions that could be a target for cationic ligands [16], [17].
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