Sentence examples for fully defective from inspiring English sources

"What you're trying to do with all this definitional stuff is to make sure you don't beat the kids down and make them think they're fully defective," he said.

Variants lacking either the SD phosphorylation sites or the SBD SH3-binding motif were able to partially restore the migration response, while only a variant lacking both signaling functions was fully defective.

However the SD mutational variant was fully defective in increasing actin assembly at the protruding leading edge and FA assembly/disassembly rates, indicating that SD phosphorylation is the sole p130Cas signaling function in regulating these processes.

This mutant is the least competent in ubiquitin-binding, but it is not fully defective.

Recent evidence suggests that YXY mutants of tetherin are impaired but not fully defective for endocytosis (Lau et al., 2011), potentially accounting for this partial phenotype.

By P45, the conditional Pcdh15Δ'CD2 mice lacked any identifiable ABR response to loud sound stimulation (115 dB SPL), indicating complete hearing loss and fully defective IHCs.

Loss of p53 also fully rescued defective cell proliferation in primary cultures of E10.5/E11.5 mesodermal tissue, performed to generate mouse embryonic fibroblast (MEF) cell lines.

Approximately one half of the fetuses can be adversely affected when a male transmits a defective fully penetrant imprinted gene silenced on the maternal allele.

It appears that overcompensation with proteases such as caspase and calpain cannot fully clear the defective tau out of the cell, at least in some cases, as with neurodegenerative disorders.

In other traits the Aatm Ore_V275A allele was able to fully rescue the defective phenotype and was indistinguishable from Aatm Aut (Fig. 2B: flight; Fig. 5: complex III and IV activity).

In this study, we demonstrate that the kidney in the VLCAD−/− mice fully compensates for a defective fatty acid oxidation most likely enhancing glucose oxidation.