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There are job-creation programs and low-cost housing, but nothing has fully ameliorated the lingering injustices.
This implies that hyperglycaemia-associated pathological retinal changes are not fully ameliorated by treatment.
Thus, the reduction in macroalbuminuria has not fully ameliorated the increased CVD risk, and a greater understanding of how to correct the processes that lead to microalbuminuria is clearly needed.
In a mouse model of focal ischemic stroke in which brain TNF levels were found to be rapidly elevated within both ipsi- and contralateral brain, 3,6′-DT fully ameliorated this rise and reduced infarct volume, neuronal death, and neurological deficits [ 112].
Inhibition of this TBI-induced rise by administration of a single dose of the TNF synthesis inhibitor 3,6′-DT fully ameliorated cognitive impairments evaluated both 7 and 30 days later; supporting both a role for TNF in TBI-induced neuroinflammation/cognitive impairment and its targeting for treatment [ 109].
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However, these improvements are unlikely to fully ameliorate it.
While the review concluded that "no drug exists to fully ameliorate or correct the cosmetic changes of HALS", the review was limited by studies with non-randomized designs and the inability to quantitatively assess the effects of specific agents.
We hypothesize that this clustering represents a limitation in the ability of bacteriophages to fully ameliorate to their host genome signature, and may be necessary for the bacteriophages to maintain host range [ 25].
We believe it is particularly important to identify these intrinsic factors, because in many cases they can be ameliorated or fully remedied by guideline authors while the guideline is being developed.
S1P-induced heat hyperalgesia was significantly ameliorated, but not fully abolished, in TRPV1−/− mice compared with wt littermates (Fig. 2D).
Removal of long branches (namely those of bivalves and patellogastropods) ameliorated but not fully resolved the problem.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com