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Their application allows full validation of methods to analyse the priority substances in "whole water" and the establishment of proficiency testing (PT) schemes [ 10, 11] to ensure that the results are correct, precise and comparable.
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However, full validation of analytical methods applied for the identification and quantification of β-carotene and CPs are rare, not to mention comprehensive and correct statistical evaluations therein.
Full validation of the method was carried out (linearity, precision, accuracy, limit of detection and limit of quantification).
In this paper, full validation of the method by comparing measurement and prediction of the rotor-alone pressure field is published for the first time.
A full validation of the method was performed, including the linearity, precision, and accuracy, as well as limits of detection and quantification.
Contrary to all other validation approaches published so far in the context of β-carotene and CPs, our groups have jointly published two comprehensive papers providing full validation of a GC-EI-MS method for volatile CPs and an UHPLC-DAD-ESI-Orbitrap MS method for non-volatile CPs and β-carotene, with preceding off-line SPE for all analytes [ 111, 116].
Here we report the development and full validation of a rapid and sensitive method based on high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS) for determination of yakuchinone A in rat plasma, as well as the use of this method to analyze samples obtained during a single oral PK study in Sprague-Dawley (SD) rats.
Therefore, a fuller validation of these methods would require a resource intensive observational study.
A full validation of the proposed approach is performed by comparing it with a standard method based on genetic algorithm.
Full validation of our approach will rely on comparing our estimates of k b and oxygen levels using other methods such as immunohistochemical staining of resected tumours.
A full validation of the process linking LPS to P2X7 upregulation is ongoing.
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