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7 8 10 Two investigators (FEK, PDM) independently screened the titles, abstracts, and full text of identified papers to determine their eligibility for inclusion (see supplementary file).
One reviewer (HIM) screened titles and abstracts, reviewed the full text of identified studies and made initial decisions on eligibility according to prespecified inclusion criteria (see online supplementary table S4).
The conventional definition for hyponatraemia of serum sodium concentration ≤135 m m was used 11, 12. Two authors (JB and MG) independently reviewed the titles, abstracts and full text of identified papers.
We found references and full text of identified studies in the medical literature, but for individual patient data we had to rely on the permission of Merck Laboratories, as data were not readily available from the principal investigators.
Abstracts and full text of identified manuscripts were reviewed and the following inclusion criteria were applied: 1) analyzed both costs and clinical outcomes, 2) provided detailed methods, and 3) involved original data analysis.
All titles, abstracts and, where required, the full text of identified reports were independently screened by X.X. and Y.J. to determine which studies satisfied the inclusion criteria, with disagreement resolved by discussion.
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Two reviewers independently reviewed the full text of studies identified for inclusion.
The abstracts and, thereafter, the full text of the identified studies were then examined to confirm the inclusion.
Stage 5 - Methodological assessment for final inclusion: This stage assesses the full text of the identified studies and judges their methodological quality.
The full text of references identified as potentially relevant were obtained.
Titles and abstracts were searched first, followed by the full text of any identified articles.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com