Sentence examples for full term development from inspiring English sources
The most striking difference between these two categories of oocytes is that only MIISN oocytes may develop beyond the 2-cell stage and reach full term development [ 23- 25].
The full term development ratio of CBHA-treated embryos was 4.2%, which is not significantly different to the control group (4.4%), suggesting CBHA treatment does not improve the full term development of porcine SCNT embryos.
Despite these promising in vitro results and histone reprogramming, the full term development was not significantly increased after treatment.
Nevertheless, unlike the improved development in vitro, full term development efficiency was hardly affected by the CBHA treatment.
Our previous study has shown that m-carboxycinnamic acid bishydroxamide (CBHA), a member of type II HDACi, could improve the in vitro and full term development of mouse SCNT embryos and improve the cell line establishment efficiency of embryonic stem cells (ES) derived from SCNT embryos (SCNT-ESCs) (Dai et al., 2010).
To determine whether CBHA could improve the full term development of porcine SCNT embryos, 2-cell stage embryos with and without CBHA treatment were transferred to the oviducts of surrogates on the day of or 1 day after the onset of estrus.
No scientist in this field is likely to question that, unless safety concerns could be allayed beyond reasonable doubt, the technique should never be used in embryos destined for full-term development.
Because of currently available prenatal screening options, pregnancies complicated by congenital anomalies are often terminated well before full-term development.
After day 30 of gestation, however, dramatic losses occurred, and only 12 out of 93 (13%) clones reached full-term development, compared to 51 out of 123 (41.6%) lambs born from the IVF control embryos.
Therefore genomic integrity of donor cells is essential for the full-term development of cloned animals.
The integrity of the genome in the donor nuclei is essential for the full-term development of such cloned animals.
