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Comments in full: Reviewer #1: The authors analyze GRNs for stability using rules from the theory of qualitative stability, particularly verifying that they do not contain directed cycles of length >= 3 and derivatives of this property.
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Full reviews:Reviewer #1: Specific points:1) Despite the authors' screening effort with >60 cloned TAARs, the vast majority of the receptors remain orphan.
Full reviews: Reviewer #1 In this manuscript, the authors addressed functional evolution of a family of olfactory receptors, an important and fascinating question given their rapid and dynamic changes in sequences and repertoires throughout animal evolution.
The full reviewers comments are shown at the end of this letter, but the points for revision boil down to the following: 1) You need to more convincingly show that light stimulation in the imaging experiments induces a significant [cAMP] increase in the sperm principal piece.
After selecting 106 articles for full review, the reviewer examined the reference sections of these articles, which resulted in a total of 12 articles that required a full review.
For the full reviews, see the Reviewers' reports section.
For the full reviews, see the Reviewers' Comments section.
All studies that appeared to fit the inclusion criteria were identified for full review by two reviewers (SJ and JS).
– confessionsofabooklover, teen reviewer Read the full review.
I have also included the full-reviewers' comments at the bottom of this letter, which contain minor issues and textual modifications that need to be addressed in the revised manuscript. 1) Your report of the 665 bp portion of the 1.3 kb sequence lacks alpha satellite, even though it was picked up on a Northern blot using alpha satellite as probes.
For full reviews, go to the Reviewers' Reports section.
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CEO of Professional Science Editing for Scientists @ prosciediting.com