Sentence examples for full receptor from inspiring English sources

Moreover, dimerization appears to be essential for the function of serotonin type 2C (5-HT2C) and type 4 (5-HT4) receptors and required to obtain full receptor activity.

Chemical modification of the antibody is necessary to enable conjugation with a drug carrier, but at the same time it is a prerequisite that while performing conjugation reactions, biological activity and full receptor binding of the antibody is maintained.

The inability of ARM390 to induce receptor endocytosis, therefore, maintained full receptor function across two sequential drug treatments.

Treatment of cells with TC led to a decrease in basal cAMP levels which reached its maximum after ∼1 min, similar to the full receptor agonist carbachol.

TRAP acts as a tethered ligand for the thrombin receptor PAR-1 and is able to cause full receptor activation in the absence of thrombin [16], [17].

In the full receptor, they slow desensitization, thereby acting as positive allosteric modulators.

Structural analysis suggests that S377-588-Fc conthenstablystably folded RBD structure, the full receptor-binding site, and major neutralizing epitopes, such that additional structures to this fragment introduce non-neutralizing epitopes and may also alter the tertiary structure of the RBD.

We sought to determine the hepatic & systemic consequence of full glucagon receptor antagonism through the study of the glucagon receptor knock-out mouse (Gcgr-/) compared to wild-type littermates.

Figure 4 shows the subnetwork from the full HIV receptor network that exhibits only the direct functional relationships between seed receptors and predicted surface membrane factors.

Compounds 24a and 24b were full μ receptor agonists, whereas compounds 25a and 25c were only partial agonists.

In some cases both the full length receptor and corresponding soluble ICD similarly affect transcription (e.g., Fz) [40], [44] whereas certain ICD's differentially affect transcription compared to their full length receptor (e.g., PC1, LRP1) [57], [57].