Cost-of-illness studies usually do not include the full range of psychosocial difficulties that actually shape the experience of persons with these disorders, affect their quality of life and determine the scope and frequency of clinical interventions.
In response to RQ1, our comprehensive literature review (Table 1) summarized for the first time the full range of published experimental design difficulties and classified five categories and 13 subcategories of difficulty on a framework that told us whether they required further research or not in order to be fully identified.
But there are no known "easy" proofs of the inequality for the full range of values, the main difficulty being near small values of s, e.g., between 2 and 4 [2].
She works with clients with a full range of issues, including anxiety, depression, relationship difficulties, sexual identity and sexual orientation issues, and history of trauma.
In practice there have been difficulties in evaluating the full range of potential outcomes and the extent to which benefits have been realised.
One possible reason that we do not obtain characterizations in the full range of Lebesgue parameters ((0,infty ]) is that new difficulties arise as soon as a Lebesgue parameter is smaller than one.
Ideally, a test should contain items with difficulty parameters well distributed across the full range of the latent phenotype and with good resolution (Figure 3).
In order to circumvent the difficulties encountered with chromium-cobalt implants, we obtained from a manufacturer the full range of a commercially available prosthesis made from non-magnetic and non-radiopaque polymer.
Despite these difficulties physiotherapists acknowledged the importance of engaging in negotiations with patients about the full range of biopsychosocial obstacles to recovery, though they did not feel they possessed adequate skills or training to deal effectively with psychosocial obstacles specifically.
The story illustrates the difficulty of changing a single element in a system without accounting for the full range of activities in which that element is embedded.
