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What has not yet been evaluated in depth is the ability many of the available PAR1 antagonists to act as either full or biased antagonists for either PAR1 or PAR2 activation.
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Furthermore, some receptors have been crystallized in different functional states in complex with antagonists, partial agonists, full agonists, biased agonists and allosteric modulators, providing further insight into the mechanisms of ligand-induced GPCR activation.
Ten minutes later, I awoke from my daze with the full (if biased) history of the Keystone XL pipeline.
You know, the people who dismiss all other outlets as full of biased lies from Hollywood Jew-fags.
The majority of existing EST data from S. salar came from highly normalized cDNA libraries that were full-length (FL) biased [ 31, 33, 48, 49].
While the dissemination of the recommendations alone will not effectively reduce dissemination bias, their full or even partial implementation should help reduce dissemination bias.
Representation in the full data set is biased, so such simple random subsets are biased as well.
Both online blogs and the mainstream media are full of unsubstantiated rumors, biased articles, and unsourced facts.
Patient outcome studies comparing residual VL to full suppression are therefore biased when using commercial assays.
Machine-learning algorithms learn from whatever is in their training data, even if their training data is full of the behaviors of biased humans.
As Joan Acocella wrote recently in The New Yorker, "Every statement is subjective, partial, full of biases and secret messages".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com