Sentence examples for full blown disease from inspiring English sources

An estimated 10-15% of otherwise healthy people who develop the full blown disease die too.

It is now believed that the cellular and molecular alterations that cause brain dysfunctions are slow in onset and that it probably takes several years to develop the full blown disease [1].

Here a clear diagnosis allows to predict severe consequences and even if the phenomenology of the disorder is not yet visible there is a 100% risk for a later development of the full blown disease.

The role of T cells in RA pathogenesis has been questioned by some, but as cited earlier it is now accepted that autoreactive T cell activation is essential in the development of the full blown disease both in human and animal models.

These mutations per se do not confer a severe loss of function of filaggrin [ 28] and in order to cause a full blown atopic disease presumably more mutations in unrelated genes (for instance genes of the immune system) as well as environmental factors are clearly needed.

Although the Sle1-bearing mice do not develop full blown lupus-like disease, the Sle1 locus has been shown to elicit lymphocyte activation and splenomegaly [ 23].

In addition, we explored the extent of complement deposition, including MAC, in a snap-shot of nerve biopsies from patients with full blown leprosy at either of the two poles of the disease spectrum, showing an association between the amount of MAC deposition and LAM immunoreactivity in nerves of leprosy patients.

Since both the weight reduction and joint inflammation are seen as the commonly manifested observations in arthritic patients and animals, therefore, we also measured these two parameters to monitor the progression of disease over a time period taken by the control arthritic rats to demonstrate full blown arthritis symptoms.

Together, these data indicated that cytoplasmic mislocalization might contribute to disease pathogenesis, although additional hits are probably required such as cellular stress or genetic/environmental risk factors to induce full blown TDP-43 pathology (112).

This grid is a full blown, counterclockwise twister.

It was a full blown freak-out.