Sentence examples for full backbone from inspiring English sources

The full backbone of OTUD2 ZnF was assigned using MARS (Jung and Zweckstetter, 2004 ).

In addition, it was possible to carry out a full backbone relaxation analysis of AR1−AR4 of IκBα, and the results reveal multiple time scales of motion centered around the binding interface in the complex with NF-κB.

In general, it is difficult to model an ideal protein design framework with the consideration of full backbone and side-chain flexibility, since there are usually a huge number of conformations that need to be sampled even for a small protein.

ODN (LabForce-InvivoGen, Nunningen, Switzerland) sequences: ODN CpG-2216: 5′-ggGGGACGATCGTCgggggg-3′, bases are phosphodiester (capital letters) or phosphorothioate (lower case); ODN CpG-2006: 5′-tcgtcgttttgtcgttttgtcgtt-3′, full phosphorothioate backbone; ODN GpC-2006: 5′-tgctgcttttgtgcttttgtgctt-3′, full phosphorothioate backbone.

[End Page 668] In essence, this otherness is propagated through a performance of the prototypical Texan (or, at least, the idea of the prototypical Texan): the straight-talking cowboy, that lonesome dove, the white man full of backbone, bravery, and bravado.

AONs with full phosphorothioate backbones and 2'O-Methyl RNA bases specific to the splice sites of human DMD exon 72, 40 and 50, and mouse Dmd exon 23 were purchased from Integrated DNA Technologies.

The sequence entropies are comparable to those of the natural sequence ensembles, as long as we take into account the full set of backbone templates.

With an effective means of generating the two key fragments 2 and 3 secured, their controlled linkage to construct the full 25-carbon backbone of leiodermatolide was now executed (Scheme  4).

Rosetta assembles these fragments into full-sized protein backbone models using various energy terms and filters.

A novel AON (novelAON57) was synthesized by Sigma-Prologo (France) with 2'-O-methyl and full length phosphorothioate backbones according to our specifications.

AON353 and AON360 against the F9 exon 2 cryptic 5′ss, and the scrambled AON, contain 2′- O-methyl modified ribonucloetides and full-length phosphorothioate backbone (36).