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Log minus log curves confirmed that the proportional hazard assumption for the Cox model was fulfilled (data not shown).
Notes: scores +, criterion fulfilled; -, criterion not fulfilled; ?, data not provided or unclear (The results of the study by van Hout et al. have not been published yet; questions 3, 7, 9 and 13 were assessed from unpublished information; questions 10 and 11 could not be assessed).
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It also alleviates the burden on the PI from having to fulfill data requests continuously".
This separation is required in order to fulfill data protection guidelines.
Except for the methodology by Neubauer et al. all methods presented above are suitable for personalized oncology research programs as they perform pseudonymization and fulfill data privacy requirements.
Such an approach may still be inadequate in trying to fulfill data request #8, where the researcher had requested a list of patients who had an orthopedic procedure performed, and were still in the therapeutic range for their International Normalized Ratio (INR; therapeutic range: 2.0-3.0) on the day of the surgery.
The Institutional Review Board of the Beth Israel Deaconess Medical Center (BIDMC) and Massachusetts Institute of Technology have approved the use of the MIMMICII database by any investigator who fulfills data-user requirements.
One reviewer (PAJ) fulfilled this data collection sheet and another (PH) checked the extracted data.
For continuous data, the assumptions for performing parametric tests were not fulfilled (the data were not normally distributed); therefore the non-parametric Kruskal-Wallis test was used.
In case that the target BER is not fulfilled, the data rate of a user u is defined to be zero, i.e., R ̄ ( u ) = 0.
When after the transformation the assumptions were fulfilled the data were analyzed by ANOVA as described before.
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