This led them to great works, but also to artists who seemed to fulfill critical prerogatives of the moment, and are less valued today.
Since that time the brigade and its subordinate units supported the XVIII Airborne Corps, fulfilling critical combat engineer, construction, topographic, and bridging missions.
All these cells fulfill critical functions, including mucociliary clearance, gas exchange and maintenance of surface tension (Morrisey and Hogan, 2010).
Gab proteins fulfill critical roles in the communication between various receptor classes and several signalling pathways involved in the control of proliferation, cell death, migration and differentiation.
Miners worked virtually unprotected, and were often treated as expendable bodies fulfilling critical roles in this important industry, which in the United States comprises about 5% of the gross domestic product.
YB-1 appears to fulfill critical cellular functions such as transcriptional upregulation of proliferation-associated and downregulation of apoptosis-related genes or induction of drug-transporter genes (like MDR-1) involved in chemoresistance [ 1, 7].
Both FV UTRs fulfill critical roles in the viral lifecycle, (Iglesias and Gamarnik, 2011) including forming base pairing interactions during strand synthesis of the viral RNA (Filomatori et al., 2006; Villordo and Gamarnik, 2009; Friebe and Harris, 2010; Villordo et al., 2010; Gebhard et al., 2011).
Inside tumor cells, YB-1 has been shown to fulfill critical cellular functions, such as the transcriptional upregulation of proliferation-associated and downregulation of apoptosis-related genes or induction of drug-transporter genes (like MDR-1) involved in chemoresistance [ 6, 20].
The United Automobile Workers union has fulfilled one critical element of the president's mandate for shared sacrifice among all parties involved in Chrysler's rescue.
In addition, intracellular iron acts as a cofactor for over 30 enzymes in this pathogen and together with zinc fulfills critical roles in the activation of enzymes involved in amino acid biosynthesis in particular [ 76].
