KEGG pathway fulfilling corrected P-value ≤ 0.05 from Bonferroni correction were defined as significantly enriched terms in DEGs.
We used the Newman Keuls test (p<0.05), a post hoc test which is already corrected for multiple comparisons, and the Greenhouse-Geisser index which allows correction for ANOVA statistics when sphericity assumptions are not completely fulfilled (this correction is used to adjust p value when df are >1).
In cases in which sphericity was not fulfilled, the Huynh-Feldt correction was used.
For testing specific hypothesis involving differential mapping of specific pathways gene expression significance was tested using t-test, or Mann Whitney U test when parametric were not fulfilled, followed by a Benjamin-Hochberg correction (False Discovery Rate, FDR).
Apart from lack of information on and correction for contamination, the quality criteria were mostly fulfilled (see supplementary table 2).
In another review of the outcomes of surgical deformity correction (osteoplasty), of 1,103 potentially relevant studies, 14 fulfilled our eligibility criteria.
Correlation type Ε: "No correlation of any type that results in numerical proximity of results, with or without correction" Condition: Νone of the previous Correlation Types is being fulfilled.
Additionally, in our study, planning objectives of the brainstem and parotids were not fulfilled in 57.5% and 70.0% of patients, respectively, for plans with pre-correction margins.
Correlation Type D: «Relative numerical proximity of original driving simulator measurements to real traffic conditions measurements, after correction following non-linear models» Condition: Νone of the previous Correlation Types is being fulfilled.
CB-SCID1 takes care of the administration (for instance ordering of questions), correction possibility in criteria judgment, suggestion of answers according to previous in-data, summing up of fulfilled criteria, and also presentation of noted diagnoses.
