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The most active compounds of the series were 7 and 16 that were p-phenylenediamine and m-aminophenol substituted derivatives to fulfill essential structural requirement, described above.
Nanocarriers can fulfill essential functions in the stabilization and delivery of drugs: they prevent solubility issues and degradation, reduce side effects and modify the pharmacokinetic profile.
While citizenship-based restrictions on certain political rights, like voting or running for office, are permissible, the commitment to fulfill essential needs and uphold access to basic opportunities is firmly established in international law.
This would mean, however, that the native TRPML3 channel does not fulfill essential detectable functions in the inner ear in vivo.
Protein and lipid kinases fulfill essential roles in many signaling pathways that regulate normal cell functions [ 1– 5].
In photosynthetic green tissues, carotenoids fulfill essential functions in photosynthesis for photosystem assembly, light harvesting, and photoprotection.
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This year, my budget will cut it again and reduce or eliminate more than 140 programs that are performing poorly or not fulfilling essential priorities.
But we come to realize, in Fisher's book, that Balanchine's "Nutcracker" -- whether televised with the mother from "Lassie" or through its infinite progeny -- embodies Kirstein's and Warburg's dream of a ballet with universal and timeless appeal, fulfilling essential human needs.
This procedure fulfilled essential requirements for the introduction of carbon-11, providing the target molecule in high yields and high radiochemical purity within 30 to 40 minutes from the end of bombardment (EOB).
Virtually all genes fulfilling essential cellular functions are early replicating.
The ubiquitin-proteasome system (UPS) fulfills essential cellular functions in eukaryotes through timely degradation of a variety of regulatory proteins.
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