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Of the 24 patients studied, 4 patients had a good response according to EULAR response criteria and 15 patients had a moderate response, while 5 patients did not fulfil response criteria [7].
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We found an activation threshold value that fulfils stability and response simultaneously.
Additionally, admissions with diseases other than severe sepsis that fulfil the systemic inflammatory response syndrome criteria (such as acute pancreatitis) may have been misclassified.
Tumours undergoing this type of response probably fulfil two important conditions: (a) the growth and survival of the vasculature is very sensitive to the agent, and (b) tumour cell survival is highly dependent on the vascular supply.
Notably, baseline ALP and AST were categorised using thresholds of ≤3x ULN and ≤2x ULN, respectively, as used in PA-I criteria 14 (incorporating higher ALP/AST thresholds), corresponding to patients with baseline biochemistry likely to fulfil at least one response criteria.
However, the more complex individual-specific odours of mammals, combined with variable responses to scents that often depend on context and learning, have led many to suggest that mammalian scent signals generally do not trigger the specific inherent responses required to fulfil the classical definition of pheromones [ 2, 4, 5].
It is unclear whether CEP-1 is functionally more related to mammalian p53 or to either of the two other mammalian p53 family members p63 and p73 that are implicated in DNA damage responses but also fulfil multiple developmental roles centred on epithelial development and neurogenesis respectively [ 9].
Thus, the observing response task immediately fulfils two of the criteria proposed by Szechtman and colleagues [16,44] to validate animal models of compulsive checking; firstly, there must be a selective increase in checking-like behaviour and, secondly, return time to the site of checking must be reduced.
Spontaneous EPSPs were defined as EPSPs that did not fulfil the criteria for an evoked response.
The questionnaires, using Likert scale and free text responses, were developed to fulfil our objectives of assessing demand, benefits of participation and programme evaluation.
Four participating centres in Europe will recruit women less than 40 years who fulfil the Bologna criteria for poor ovarian response.
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