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For this reason, Lewis often refers to the material as "fugitive ink".
The last dispenser contained the fugitive ink that Lewis had developed to create channels within materials.
The dispenser with the fugitive ink moved quickly and almost imperceptibly, releasing an exceptionally thin stream of what looked like agar onto the glass slide.
Crucial to Lewis's project is what she calls fugitive ink, which liquefies when cooled, leaving behind a hollow canal that can be filled with cells.
The fugitive ink is then removed to create vascular channels in the extracellular matrix composition, thereby forming an interpenetrating vascular network in a tissue construct.
One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns.
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Fugitive inks, such as watercolors, fade when exposed to light, and moisture can wreak havoc on pigments.
Therriault, D., Shepherd, R. F., White, S. R. & Lewis, J. A. Fugitive inks for direct-write assembly of three-dimensional microvascular networks.
These developments include 1) novel printing regimes have been enabled by the use of fugitive inks for the creation of intricate structures e.g. vascularized tissue constructs; 2) mechanical strength of printed constructs can be enhanced by co-printing soft and hard biomaterials; 3) bioprinted in-vitro models for drug testing applications are closer to reality.
1959 The Fugitive Kind.
Lewis and her team have developed new classes of concentrated colloidal, fugitive organic, polymer, hydrogel, and sol-gel inks for pen-on-paper, inkjet, roll-to-roll and 3D printing.
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