Sentence examples for fuel neurons from inspiring English sources
Thus oxidation of fatty acids by astroglial mitochondria provides energy and part of the carbon skeleton for the anaplerotic synthesis of neuromediators and saves glucose, which is converted either into lactate to fuel neurons, or stored for emergency as glycogen.
Some lactate released from activated cells and retained in tissue may be used as oxidative fuel for neurons and astrocytes.
In addition, both lactate and glycerol can be transported by AQP9, and both substances can be used as fuel by neurons [ 29, 30].
The favorable activities of exenatide probably rely on the induction of a metabolic switch toward anaerobic glycolysis as well as increased production of lactate, two phenomena that can fuel the neurons of brains in which a valid cognitive reserve is still present.
Glucose is the predominant cerebral energetic compound, fueling both neurons and astrocytes [ 36].
This increase in brain activity naturally increases the brain's need for nutrients, but until recently, scientists hadn't fully understood how neurons fuel themselves during exercise.
Thus astrocyte lactate production may act as an energy fuel reserve for neurons, maintaining their electrical activity during hypoglycaemia [ 1].
The major fuel for activated neurons and the models for neuron astrocyte interactions have been controversial because discordant results are obtained in different experimental systems, some of which do not correspond to adult brain.
We have previously investigated the relative roles of extracellular glucose and lactate as fuels for glutamatergic neurons during synaptic activity.
In short, astrocyte-to-neuron lactate shuttling and use of glucose-derived lactate as a major neuronal fuel during activation lack strongly supportive in vivo data.
Astrocytes also store energy in the form of glycogen that can be metabolized to pyruvate for their own survival or to lactate for export to neurons for additional fuel during energy crises, such as during H/I (Swanson and Choi, 1993).
