The mean time from beginning of postresection neck imaging (including imaging of positive and negative pathology specimens) to confirmation of intraoperative frozen section pathology analysis or IOPTH results was 16 ± 5 minutes (range 7 26; n = 18) and 37 ± 4 minutes (range 12 91; n = 21), respectively.
The mean time from the beginning of specimen imaging (including imaging of positive and negative pathology specimens) to confirmation of intraoperative frozen section pathology analysis or IOPTH results was 21 ± 1 minutes (range 11 36; n = 26) and 45 ± 4 minutes (range 27 96; n = 23), respectively.
Frozen section pathology of the bladder neck was performed to ensure a safe margin.
A right para-aortic lymph node dissection was carried out routinely for staging purpose in pancreatic head tumours and followed by pancreaticoduodenectomy in case no metastatic lymph nodes were found at frozen section pathology.
Intraoperative frozen section pathology revealed that the cyst was composed of mature teratomatous elements including epidermis, sebaceous glands, adipose, normal thyroid tissue (>50%) and a 10 mm non-encapsulated cancerous focus (which was confirmed later to be the FV-PTC on final pathology, Figure 1a and 1b) [ 10- 12].
Once assessed by a pathologist, the portion acquired for tissue banking was excised, and snap frozen in the pathology lab.
For patients randomized to TORS, the main specimen will be taken to pathology frozen section room and a portion from the center of the specimen will be taken with the assistance of the pathologist and frozen at -80 degrees Celsius.
Therefore, our MBTB samples were derived in all cases from a pathology resection specimen that at the time of surgery was rapidly assessed by the pathologist and both mastectomies and lumpectomies were dissected and sampled immediately (mean time approximately 50 minutess) to obtain a fresh tumor sample that was then frozen in the pathology laboratory.
All samples were snap frozen in the institutional pathology departments immediately upon arrival.
Anatomic pathology rotations include surgical pathology (individual rotations listed below), frozen section, Hot Seat (preliminary diagnosis and triage), and autopsy pathology.
